Dichlorine oxide Subject

Dichlorine h ptoxide, CljO, is the most stable of the chlorine oxides. It is a yellow oil at room temperature, b.p. 353 K, which will explode on heating or when subjected to shock. It is the anhydride of chloric(VlI) acid (perchloric acid) from which it is prepared by dehydration using phosphorus(V) oxide, the acid being slowly reformed when water is added. 

On the basis of a similar chlorination strategy, an asymmetric approach to undecachlorosulfolipid (mytilipin B) 93, a far more complex sulfolipid, was recently disclosed by the same group (Scheme 43.14). The synthesis began with the diastereoselective dichlorination of diene 101 with Et4NCl3 to afford dichloride 102 in 66% yield with 1.8 1 diastereo-selectivity. Then, (Z)-alkenyl epoxide 103 derived from 102 was subjected to dichlorination with Et4NCl3, followed by deprotection and oxidation, to deliver fragment A 104 in... 

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