Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Phenytoin Diazoxide

Diazoxide Phenytoin Altered relation between total phenytoin concentration and effect Displacement from plasma protein binding sites... [Pg.294]

Highly protein-bound drugs In vivo, raloxifene did not affect the binding of warfarin, phenytoin, or tamoxifen. However, use caution when raloxifene is coadministered with other highly protein-bound drugs, such as diazepam, diazoxide, and lidocaine. [Pg.190]

Disulfiram-like reaction with ritonavir, tipranavir, diazoxide Increases levels and toxicity of tacrolimus, cyclosporine, lithium, and phenytoin... [Pg.59]

VASODILATOR ANTI HYPERTENSIVES ANTIEPILEPTICS Co-administration of diazoxide and phenytoin l phenytoin levels and possibly 1 efficacy of diazoxide Uncertain at present Monitor phenytoin levels and BP closely... [Pg.41]

Ceftriaxone (A) Clindamycin (A) Clofibrate (A) Dexamethasone (N) Diazepam (B) Diazoxide (A) Dicloxacillin (N) Digitoxin (N) Etoposide (N) Ibuprofen (A) Indomethacin (A) Nafcillin (A) Naproxen (A) Oxacillin (A) Phenylbutazone (A) Phenytoin (A) Probenecid (A) Salicylic acid (A) Sulfisoxazole (A) Teniposide (N) Thiopental (A) Tolbutamide (A) Valproic acid (A) Warfarin (A)... [Pg.3031]

Noninterfering acetaminophen, acetazolamide, albuterol, amitriptyline, amobarbital, car-bamazepine, diazoxide, disopyramide, ethosuximide, isoproterenol, nitrazepam, nortriptyline, oxazepam, pentobarbital, phenobarbital, phenytoin, primidone, procainamide, salicylic acid, sulthiame... [Pg.1353]

Simultaneous acetaminophen, acetanilide, N-acetylcysteine, N-acetylprocainamide, amo-barbital, aspirin, barbital, butabarbital, butalbit, caffeine, carbamazepine, cimetidine, codeine, cyheptamide, diazoxide, diflunisal, disopyramide, ethchlorvynol, ethosuximide, gentisic acid, glutethimide, heptabarbital, hexobarbital, ibuprofen, indomethacin, keto-profen, mefenamic acid, mephenytoin, mephobarbital, methaqualone, methsuximide, methyl salicylate, methypiylon, morphine, naproxen, nirvanol, oxphenylbutazone, pentobarbital, phenacetin, phenobarbital, phensuximide, phenylbutazone, phenytoin, primidone, procainamide, salicylamide, secobarbital, sulindac, thiopental, tolmetin, trimethoprim... [Pg.1442]

Effects are enhanced by other diuretics. Profound hypotension occurs with other antihypertensives. Diazoxide displaces warfarin and phenytoin from albumin. [Pg.71]

A child receiving phenytoin 29 mg/kg daily and an adult receiving phenytoin 1 g daily were unable to achieve therapeutic phenytoin serum levels while taking diazoxide. When the diazoxide was withdrawn, satisfactory serum phenytoin levels were achieved with dosages of only 6.6 mg/kg and 400 mg daily, in the child and the adult, respectively. When diazoxide was restarted experimentally in the adult, the serum phenytoin levels became undetectable after 4 days, and seizures occurred. Two other reports describe this interaction. " In addition it appears that the effects of the diazoxide can also be reduced. ... [Pg.557]

What is known suggests that diazoxide increases the metabolism and the clearance of phenytoin from the body. The half-life of diazoxide is possibly reduced by phenytoin. ... [Pg.557]

Information is limited to these reports, but the interaction would appear to be established. Monitor the effects of concurrent use, being alert for the need to increase the phenytoin dosage. The clinical importance of the reduced diazoxide effects is uncertain. [Pg.557]

Three children and one adult had veiy marked reductions in serum phenytoin levels when diazoxide was given, and in one case... [Pg.557]

See other pages where Phenytoin Diazoxide is mentioned: [Pg.939]    [Pg.844]    [Pg.939]    [Pg.844]    [Pg.131]    [Pg.108]    [Pg.131]    [Pg.1402]    [Pg.108]    [Pg.131]    [Pg.1221]    [Pg.434]    [Pg.557]    [Pg.54]   
See also in sourсe #XX -- [ Pg.557 ]

See also in sourсe #XX -- [ Pg.54 ]



SEARCH



Diazoxide

Phenytoin

© 2024 chempedia.info