Diazotization nitration during

Subs tituted-1,2,3-oxadiazolo[4,5-/]quinoline 47 originated after nitration, reduction, and diazotization of alkaloid quinine during the study of its stmcture and reactions (53RZC495, 54RZC61). 

Similar nucleophilic substitutions of other groups during diazotizations (chloro-de-nitrations) were found by Oku and Matsui (1979) and Trimmer et al. (1985). 

Nitration, suggested to involve nitrosation/oxidation, occurs during diazotization of some substituted 2-amino-1,8-naphthyridine derivatives (15).41 The selectivity of this process was contrasted with that of the nitronium ion reaction. 

Other 3-substituted morphinans were isolated during attempts to prepare 3-hydroxymorphinans by sequential nitration, hydrogenation to the amine, and diazotization of the unsubstituted precursor/381 A mixture of 2- and 3-nitromorphinans was isolated, but no biological data were reported. 

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