2-Diazopropane, imidates, cycloaddition

The 2-diazopropane 59 reacts at 0 °C in dichloromethane with the imidate 60a to give exclusively the adduct 61a after 10 h of reaction. This compound results from the regioselective 1,3-dipolar cycloaddition of the 2-diazopropane to the imidate C - N bond (Scheme 13). 

In conclusion, we have been successful in developing a new method for the synthesis of [ 1,2,3]-triazoles by regioselective 1,3-dipolar cycloaddition of 2-diazopropane with imidates 60 in good yields. 

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