1.1- diaryl-2-propyn

Syntheses of l-aryl-3,3,3-trilluoro-l-propynes and their reactions with nitrile oxides to give 3,5-diaryl-4-tri(luoromethylisoxazoles have been carried out. In particular, l-(4-chlorophenyl)-3,3,3-trilluoro-l-propyne, on reaction with 4-chlorobenzohydroximoyl chloride in the presence of Et3N in PhMe, give a 45% mixture of 211 (R = R1 = 4-CIC6H4) and the regioisomer 212 in the ratio of 97 3, respectively (370). 

Keywords l,l-diaryl-2-propyn-l-ol, 2-naphthol, silica gel, TsOH, naphthopyran... 

Two structural modifications of 3 leads to 9-(1-propyn-yl)-9-fluorenol derivatives ( ) and 2,5-diaryl-l,4-hydro-quinones (J ), ... 

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