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2,4-Diamino-6-phenyl-l,3,5-triazine

Phenylguanamine (2,4-diamino-6-phenyl-l,3,5-triazine) is synthesized from benzonitrile and dicyanamide ... [Pg.507]

Like acetonitrile, benzonitrile is a powerful solvent fnr many inorganic and organic materials including some polymers. It can be converted to a large number and variety of derivatives by simple syntheses e.g.. by hydrolysis, it can be converted to either benzoic acid nr benzamicle. The most important reaction is with dicyandiamide to produce 2,4-diamino-6-phenyl-l,3,5-triazine (benzogunnamine) ... [Pg.1080]

Diamino-6-(2-methoxyethyl)-l,3,5-triazine 2-Amino-4-ethyl-l,3,5-triazine 2-Amino-4-phenyl-l,3,5-triazine 2-Amino-4-ethyl-6-methyl-l,3,5-triazine... [Pg.13]

Scheme 6.266 Synthesis of 4,6-diamino-2,2-dimethyl-l,2-dihydro-l-phenyl-l, 3,5-triazines. Scheme 6.266 Synthesis of 4,6-diamino-2,2-dimethyl-l,2-dihydro-l-phenyl-l, 3,5-triazines.
Hopfinger also examined a set of derivatives of 2,4-diamino-6-dimethyM-phenyl-l,3,5-triazine, of which the 4-chloro-derivative, cycloguanil (3.35), is an outstanding anti-malarial drug. Here, C refers to 50% inhibition of DHF reductase from a mammalian tumour. The 35 examples covered a 10000-fold spread in inhibition. Better correlations were obtained with than with V, the... [Pg.639]

Thiazol 2-(4,6-Diamino-l,3,5-triazin-2-ylamino)-4-phenyl- -Hydrobromid E8b, 54 (Het —NH2—CS-NH2 +... [Pg.990]

Methiotriazamine, l,6-Dihydro.6.6.dimethyl-I-[4-(methylthio pkenytJ-l,3tS-triazine-2,4-diamine 4.6-di-amino-I,2-dihydrO-2,2-dimetbyl l-[p-[Pg.943]

The role of drug-membrane interactions in overcoming, or at least in reducing, resistance will be discussed using two examples of antibacterials. A series of 5-(substituted) benzyl-2,4-diaminopyrimidines and 4,6-diamino-l,2-dihydro-2,2-dimethyl-l-(3-substituted)phenyl-s-triazines, inhibitors of dihydrofolate reductase (DHFR), were tested against sensitive and resistant E. coli cell cultures as well as against E. coli-derived DHFR [55] and compared with the effect on sensitive and resistant murine tu-... [Pg.241]

Diamino-6-(2,3-dichlorophenyl)-l,2,4-triazine (Lamotrigine (10) as methanol solvate) <89CSC129>, 3-(but-3-ynylthio)-l-ethyl-5-phenyl-l,2,4-triazinium tetrafluoroborate (11) <89T6499>,... [Pg.510]


See other pages where 2,4-Diamino-6-phenyl-l,3,5-triazine is mentioned: [Pg.224]    [Pg.417]    [Pg.224]    [Pg.259]    [Pg.345]    [Pg.85]    [Pg.86]    [Pg.224]    [Pg.417]    [Pg.13]    [Pg.100]    [Pg.418]    [Pg.353]    [Pg.615]    [Pg.74]    [Pg.224]    [Pg.417]    [Pg.224]    [Pg.259]    [Pg.345]    [Pg.85]    [Pg.86]    [Pg.224]    [Pg.417]    [Pg.13]    [Pg.100]    [Pg.418]    [Pg.353]    [Pg.615]    [Pg.74]    [Pg.172]    [Pg.339]    [Pg.354]    [Pg.52]    [Pg.352]    [Pg.425]    [Pg.7]    [Pg.82]    [Pg.164]    [Pg.614]    [Pg.220]   
See also in sourсe #XX -- [ Pg.353 ]




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4.6- Diamino-1,3,5-triazines

5- -l,2,4-triazine

Phenyl-l,3,5-triazine

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