Dialysis apparatus, continuous

Fig. 4 Continuous dialysis apparatus for the parallel purification of up to twelve samples...

A significant leap forward was made in 1988 by Spirin et al. [4], who developed a continuous-flow apparatus for the continuous supplementation of reaction mixtures with substrates required for protein synthesis and continuous removal of reaction by-products. In this way, it was shown that the activity of a cell-free system could be sustained for many hours, compared with batch-mode reactions which became inactive after approximately 45 minutes. Since then, many reports have been made describing the use of simple dialysis systems [3, 5] that can maintain the high productivity of a reaction over many hours, without the use of a cumbersome apparatus. 

Apparatus for Dialysis. Beside Graham s dialyzer, already described on page 7, Several others are in use. Generally a membrane is stretched across an open vessel and the whole partially submerged in a larger vessel filled with distilled water as in Fig. 4. If continuous... 

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