Diabetes mellitus foot infections

Foot ulcers and related infections are among the most common, severe, and costly complications of diabetes mellitus (DM). Fifteen percent of all patients with DM develop at least one foot ulcer, resulting in direct health care expenditures of approximately 9 billion annually in the United States.26,27 Diabetic foot ulcers and wounds are highly susceptible to infection. Related skin, soft tissue, and bone infections account for 25% of all diabetes-related hospitalizations.28 More than half of all nontraumatic lower extremity amputations (LEAs) performed each year in Western nations are linked to diabetic foot infection 80,000 LEAs are performed annually in the United States alone.29,30... 

Diabetic wound is a complication of diabetes mellitus which is characterised by the slow healing of normal wounds specially produced at the body extremities leading to diabetic foot ulceration etc. It leads to approximately 20% cases of hospitalisation, amputations, morbidity and 50% of non-traumatic lower limb amputations [10, 11]. Diabetic wounds are accelerated by the microorganisms like Staphyloccocus aureus. Pseudomonas, Streptococci etc. [11]. Medicinal plants have been extensively used for thousands of years to cure ailments like diabetes, blood pressure, infection etc. Herbal, Unani, Chinese, traditional or folklore all state the beneficial effects of such plants [12, 13]. 

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