Dewetting in MIMIC

MIMIC is a simple and versatile soft lithographic method introduced by Whitesides et It is suitable for fabricating complex 

In particular, in the masters for MIMIC the motif consists of protruding lines that become grooves in the replica. When the stamp is placed in contact with a surface, the grooves form capillary channels. The size of the channels together with the concentration of the solution and the self-organization properties of the solute determine the length scale that can be achieved with this process. When a solution is poured at the open end of the stamp, the liquid spontaneously fills the channels under the effect of capillary 

In order to apply MIMIC at a large scale, control 

In diluted DNA solutions the repulsive electrostatic interaction, between DNA molecules and the surface, is shielded by the buffer, therefore a homogeneous continuous layer with salt and DNA can be deposited. The transition from continuous lines to split strings of dots at higher DNA concentration arises either from the dewetting of initially continuous stripes or nucleation and growth in a partial wetting regime.  

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