Deuterium isotope effect, electrochemical

N-Hydroxyphthalimide A-Hydroxyphth-alimide (NHPI) was shown to be a mediator for the electrochemical oxidation of (1) to (2) (Eq. 6) [57, 58], although the yields of (2) were not always satisfactory. A large deuterium isotope effect ( h/ d = 10.6) was observed in the oxidation of benzhydrol [59]. Recently, tetrafluoro-NHPI was found to be efficient for the oxidation of borneol [60]. 

Another result of the cold-fusion epopee that was positive for electrochemistry are the advances in the experimental investigation and interpretation of isotope effects in electrochemical kinetics. Additional smdies of isotope effects were conducted in the protium-deuterium-tritium system, which had received a great deal of attention previously now these effects have become an even more powerful tool for work directed at determining the mechanisms of electrode reactions, including work at the molecular level. Strong procedural advances have been possible not only in electrochemistry but also in the other areas. 

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