Deuterated compounds Hydrogen chloride

The results for the deuteration of 2-, 3-, and 4-picolines are summarized in Table IX. With 2-picoline, specific deuteration in the a-position only is observed on cobalt, whereas platinum is catalytically active for all positions,105 as is nickel chloride which catalyzes deuteration of the methyl group in particular. As with pyridine, borohydride-reduced oxide catalysts are more active than self-activated preparations. The much higher reactivity in 2-picoline compared with pyridine in selfactivation indicates that the methyl group compensates for deactivation from the nitrogen lone pair. Hydrogen for self-activation in the former compound originates predominantly from the methyl group. 

Hydrogenation of olefins on a soluble catalyst has been reported recently [61,62]. Tris(triphenylphosphine)rhodium chloride [(Ph3P)3RhCl] will promote homogeneous hydrogenation of reactive double bonds, including the A -bond in Ai -dien"3-ones, where the product of deuteration was the ia,2a-dideutero-compound (17) [62]. The mechanism is not... 

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