Single molecule fluorescence experiments detectors for

The choice of detector is another critical stage in the development of a single molecule fluorescence experiment. In general the detector should flalfil the following 

PMT Multi-photon diffusion FCS/PCH [73] Single-photon diffusion detection / FCS [11 ] 

ICCD/EMCCD Stoichiometry determination [62] GFP Imaging In cells [9] Nucleotide kinetics [67] Combined TIRF/AFM [72] 

CMOS array Parallel single molecule detection/FCS [64] 

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