Desire and Prandi

In a rather comprehensive work aimed at synthesizing diverse carbapentofuranoses, Desire and Prandi [8] exploited a cobalt-catalyzed radical cyclization/oxygenation of a wide number of 6-iodohex-l-enitols to assemble the carbocyclic frame of the targets. As an example, Scheme 4 displays how 4a-carba-a-D-arabinofuranose 27 was prepared by starting with readily available glucopyranoside 24. 

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