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Escitalopram Desipramine

ANTIDEPRESSANTS-duloxetine, modobemide, SSRIs - escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, TCAs - amitriptyline, clomipramine, desipramine, doxepin, imipramine... [Pg.280]

At 20 mg/day of escitalopram (twice the recommended daily starting dose), there is some elevation in levels of coadministered desipramine and metoprolol, which appear comparable to the effect of RS-citalopram.i i 2°... [Pg.37]

Although studies in vitro did not reveal an inhibitory effect of escitalopram on CYP2D6, limited in vivo data with desipramine , (p.l241) and metoprolol , (p.855) suggest a modest inhibitory effect. The UK manufacturer recommends caution if escitalopram is given with drugs that are mainly metabolised by this enzyme, and that have a narrow therapeutic index. They specifically name fleeainide. ... [Pg.260]

Escitalopram 20 mg daily for 21 days increased the maximum serum levels and AUC of a single 50-mg dose of desipramine by 40% and 100%, respectively. The UK manufacturers predict that clomipramine and nortriptyline will be similarly affected. ... [Pg.1241]

See other pages where Escitalopram Desipramine is mentioned: [Pg.497]    [Pg.165]    [Pg.276]    [Pg.359]   
See also in sourсe #XX -- [ Pg.1241 ]



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