Design of Immunomodulating Drugs

Given the importance of immunomodulators, this is a drug design area that is too important to be left to the vagaries of serendipity. The cytokines represent the best hope for rational drug design in the area of immunomodulation. 

Chemokines—cytokines that regulate leukocyte movement 

Interferons (IFN)—cytokines that modulate ( interfere with) leukocyte function 

Interleukins (IL)—cytokines that mediate communication between leukocytes 

Tumour necrosis factors (TNF)—cytokines that are immunotoxic to tumors and bacteria 

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