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Dendronized Supports for Multivalent Molecular Recognition

Glycoside-decorated amino-ether dendrons of up to third generation were prepared in solution and subsequently covalently immobilized on alumina chip by Pieters, Liskamp, and coworkers.The study of the binding of fluorescence-tagged lectins to the glycoclusters on the chip revealed the multivalency enhancement of the binding. [Pg.468]

DENDRITIC MOLECULES ON SOLID SUPPORT SOLID-PHASE SYNTHESIS AND APPLICATIONS [Pg.470]

Differences in the extent of this enhancement for different lectins were attributed to the variations in the distance between the binding sites on the lectins. [Pg.470]


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Dendrons

Dendrons/dendronized

Molecular recognition

Molecular support

Multivalency

Multivalent

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