Denaturation and Renaturation are Sharp Cooperative Transitions, with Latent Heat

4 Denaturation and Renaturation are Sharp Cooperative Transitions, with Latent Heat 

Privalov discovered, that protein denaturation, when it is caused by elevating temperature, requires some latent heat, just like melting of a solid, and in about the comparable amount per unit mass knowing the latent heat per unit mass of ice melting and the molecular mass of each amino acid monomer (around 110 Dalton), you can estimate the latent heat of denaturation for a typical protein of about 200 amino acids, it 

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