Deming regression analysis weighted

Figure 14-30 An example of application of weighted Deming regression analysis.The solid line is the estimated regression line, and the dotted line is the line of identity.The estimated 95% confidence bands obtained by the jackknife approach are the curved dashed lines.

Example of Application of Regression Analysis (Weighted Deming Analysis)... 

TABLE 14-12 Results of Weighted Deming Regression Analysis for the Comparison of Drug Assays Example, N - 65 (xl,x2) Measurements... 

Table 14-14 covers application of weighted Deming regression analysis in situations with proportional SDs (constant CVs) and includes intervals with range ratios extending from 2 to 100. The standardized slope deviation is here ... 

Let us now consider the conditions an analytical measurement range of 600 mg/L to 3000 mg/L (i.e.> a range ratio of 5) the midpoint of the interval (x, ) = 1800 mg/L and for both methods, proportional SDaS with CVaS = 0.03, The regression procedure is weighted Deming regression analysis with a significance level (Type I error) of 5% and a statistical power of 90%. 

Sample size for weighted Deming regression analysis Equivalent sample size for unweighted Deming regression analysis for slope testing... 

Figure 14-29 Distances from data points to the line in weighted Deming regression assuming proportional random errors in xl and x2.The symmetric case is illustrated with equal random errors and a slope of unity yielding orthogonal projections onto the line. (From Linnet K. Necessary sample size for method comparison studies based on regression analysis. Clin Chem 1999 45 882-94.)...

---