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Delayed drug reactions diagnosis

One case report of a drug reaction with eosinophilia and systemic symptoms (DRESS) was attributed to amikacin treatment of a septic arthritis. Patch testing and the presence of circulating amikacin sensitive T-cells confirmed the diagnosis [6 ]. Delayed-type hypersensitivity reactions are possible with all medicabons given and should be considered in a subject with prominent eosinophilia and systemic symptoms who are not responding as expected to treatment. [Pg.364]

Answers to questions 3, 4, 5, and 7 can go a long way toward helping to establish a firm diagnosis. In relation to points 4 and 5, information on the temporal sequence of events can provide essential information needed to help determine the mechanism of the reaction. Immediate, IgE-antibody-mediated reactions that can range from a simple rash to full-blown anaphylaxis generally occur from only a few minutes to 1 h after drug administration. Delayed or late reactions may occur from more than 1 h up to several days after... [Pg.92]


See other pages where Delayed drug reactions diagnosis is mentioned: [Pg.730]    [Pg.146]    [Pg.79]    [Pg.91]    [Pg.118]    [Pg.122]    [Pg.126]    [Pg.174]    [Pg.337]    [Pg.355]    [Pg.387]    [Pg.456]    [Pg.289]    [Pg.798]    [Pg.877]    [Pg.234]    [Pg.13]    [Pg.14]    [Pg.121]    [Pg.122]    [Pg.123]    [Pg.199]    [Pg.235]    [Pg.312]    [Pg.332]    [Pg.343]    [Pg.356]    [Pg.392]    [Pg.395]   
See also in sourсe #XX -- [ Pg.337 ]




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