Degradation of Collagen and Stromal Proteins

Catalytic domain with active site cleft (orange), catalytic zinc (red) and 2 structural calcium ions 

Hemopexin-like domain with four-fold blade-like symmetry 

Protease elass MMP number Keratinoeyte leukocyte expression 

Macrophage precursors that develop from the white blood cell infiltrates at sites of stromal injury or infection 

MMP= Enzyme name Molecular mass, latent fkDa) Molecular mass, active (kDa) Substrates 

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