Degradation indicator

The presence of markers of thrombin generation, thrombin activity, and fibrin (fibrinogen) degradation indicates that... 

L-Rha, a-L-Rhap-(l- 2)-L-Fuc, a-L-Fucp-(l- 3)-L-Fuc, and /3-d-GlcpA-(l- 4)-L-Fuc. The isolation of 2-O-a-L-rhamnopyranosyl-D-erythritol after a Smith degradation indicated an a-L-Rhap-( 1— 4 )-/3-d-GlcpA-(l- 4 )-L-Fucp sequence.173... 

Active transport mechanisms exist in the gastrointestinal tract and other epithelial sites, for the absorption of di- and tri-peptides. As described above, a greater understanding of the molecular specificity of this carrier could provide important leads for the delivery of peptides. Proteins and large peptides may be transported across cells via endocytic processes. Transcytosis is achieved if the endocytic vesicles can reach the basal membrane without fusion with lysosomes. However, various studies have shown that in the majority of cases the internalized protein is degraded, indicating that the transcytotic pathway is a minor one and most of the endocytosed protein is subject to lysosomal degradation. 

Keywords Chromatographic fingerprinting Degradation Indicator products ... 

P, P ] Inouye and co-workers documented that the addition of the morpholine enamine of cyclohexanone to ( —)-menthyl crotonate proceeds with detectable asymmetric induction (Scheme 10) (21). Although the level of face selection was not determined, degradation indicated that the S enantiomer is the preferred product. 

The possible origins of rings a, b, and c are illustrated for the alkaloids decodine (19) and decinine (20) (Scheme 4). Both [2- C]-DL-lysine and [6- C]-DL-lysine were incorporated into these alkaloids in Decodon verticillatus Degradation indicated that lysine was utilized as an intact C5N unit and, further, a symmetrical intermediate was involved. [l- C]Lysine gave totally inactive alkaloid. 

S. isatidens led independently to the same conclusion about the origin of the Cio necic acids degradation indicated a common origin for both halves of retronecic and senecic acids. 

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