Dealing with missing data

Data Stating which data are to be included, the data input format required by NONMEM, how to deal with missing data, and how to handle outhers 

F. Arteaga, A. Ferrer, Dealing with missing data in mspc several methods, different interpretations, some examples. Journal of Chemometrics 16 (2002) 408-418. 

B. Walczak, D. Massart, Dealing with missing data Part i, Chemometrics and Intelligent Laboratoy Systems 58 (2001) 15-27. 

A number of approaches to dealing with missing data are described by Molenberghs and Kenward (2007). 

Walczak, B. Massart, D.L. (2001). Dealing with missing data Part I and Part II. Chemometrics and Intelligent Laboratory System. Vol. 58, pp. 15-27 and pp. 29-42. ISSN 0169-7439 

There are a number of alternative approaches to dealing with missing data in common practice. Amongst these are the following  

While there are widely accepted methodologies for dealing with missing data, it is certainly 

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