Daunomycin temperature dependence

Figure 26. The temperature dependence of the 360-MHz proton NMR spectra (4.5 to 9.0 ppm) of the daunomycin poIy(dA-dT) complex, Nuc/D =25, in /M NaCl, lOmM cacodylate, ImM EDTA, 2H.O, pH 6.5 between 69° and 88°C. The daunomycin resonances are designated by an asterisk.

Figure 27. The temperature dependence of the adenosine H-2 resonance (7.1 to 8.1 ppm) for poly(dA-dT) ( ) and the daunomycin poly(dA-dT) complexes, Nuc/D = 50 (A), 25 (O), 9 ( ), and 5 (A.) in IM NaCl, lOrnM cacodylate, 7mM EDTA, HjO solution. The poly(dA-dT) concentration was fixed at I9.3mM in phosphates and the daunomycin concentration was varied to make the different...

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