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Dacarbazine extravasation

The antidote of choice for mechlorethamine extravasations is sodium thiosulfate. This agent binds alkylating agents, resulting in neutralization to inactive compounds that are then excreted. Sodium thiosulfate also may be effective for high-concentration cisplatin or dacarbazine extravasations. [Pg.1491]

Dacarbazine (DTIC) -atypical alkylating agent, noncell cycle dependent -bone marrow suppression -nausea and vomiting -vesicant if extravasated -flu-like syndrome -fever... [Pg.170]

See other pages where Dacarbazine extravasation is mentioned: [Pg.24]    [Pg.24]    [Pg.25]    [Pg.96]    [Pg.131]    [Pg.132]    [Pg.136]    [Pg.136]    [Pg.137]    [Pg.1169]    [Pg.866]    [Pg.106]   
See also in sourсe #XX -- [ Pg.1489 , Pg.1491 ]

See also in sourсe #XX -- [ Pg.106 ]



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Dacarbazine

Extravasation

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