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Cytotoxic/protective activity

Cytotoxic/Protective Activity of Nitric Oxide in Cancer... [Pg.133]

Fig. 7.1 Schematic representation of the cytotoxic/protective roles of NO in cancer. The complicated outcome of cytotoxic/protective activity of NO depends on the concentration of NO and microenvironment with tumor cells and tumor-associated macrophages. High concentrations of NO, principally induced by iNOS, may induce anti-cancer effects in tumor cells, whereas low, but continuous, concentrations of NO, mainly induced by eNOS, may result in pro-cancer effects. NO has also the potential to enhance both radiotherapy and chemotherapy... Fig. 7.1 Schematic representation of the cytotoxic/protective roles of NO in cancer. The complicated outcome of cytotoxic/protective activity of NO depends on the concentration of NO and microenvironment with tumor cells and tumor-associated macrophages. High concentrations of NO, principally induced by iNOS, may induce anti-cancer effects in tumor cells, whereas low, but continuous, concentrations of NO, mainly induced by eNOS, may result in pro-cancer effects. NO has also the potential to enhance both radiotherapy and chemotherapy...
Behera BC, Sonone A, Makhija U (2009b) Protoplast isolation from cultured lichen Usnea ghattensis, their fusion with protoplasts of Aspergillus nidulans, fusant regeneration and production of usnic acid. Folia Microbiol 54 415-418 Behera BC, Mahadik N, Morey M (2012) Antioxidative and cardiovascular-protective activities of metabolite usnic acid and psoromic acid produced by lichen species Usnea complanata under submerged fermentation. Pharm Biol 50 968-979 Bezivin C, Tomasi S, Rouaud I et al (2004) Cytotoxic activity of compounds from the lichen Cladonia convoluta. Planta Med 70 874-877... [Pg.196]

See other pages where Cytotoxic/protective activity is mentioned: [Pg.862]    [Pg.863]    [Pg.542]    [Pg.669]    [Pg.199]    [Pg.218]    [Pg.224]    [Pg.314]    [Pg.186]    [Pg.73]    [Pg.257]    [Pg.490]    [Pg.431]    [Pg.272]    [Pg.295]    [Pg.389]    [Pg.12]    [Pg.45]    [Pg.57]    [Pg.113]    [Pg.242]    [Pg.282]    [Pg.188]   


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Cytotoxic/protective activity cancer

Cytotoxic/protective activity tumor cells

Cytotoxicity activities

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