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Cytochrome P450 liability

Not an inducer or inhibitor of cytochrome P450 enzyme low drug interaction liability... [Pg.195]

Zuegge, J., el al. A fast virtual screening niter for cytochrome P450 3A4 inhibition liability of compound libraries. QSAR 21 249-256. 2002. [Pg.64]

Zuegge, J., Fechner, U., Roche, O., Parrott, N.J., Engkvist, O. and Schneider, G. (2002) A fast virtual screening filter for cytochrome P450 3A4 inhibition liability of compound libraries. Quant. Struct. -Act. Rdat., 21, 249-256. [Pg.1208]

Cytochrome P450 (CYP) enzymes can be induced by many xenobiotics including some drugs through the mediation of nnclear receptors. Understanding CYP induction potential of an NCE is important to minimize the drug-drug interaction liability. [Pg.85]

See other pages where Cytochrome P450 liability is mentioned: [Pg.2]    [Pg.12]    [Pg.380]    [Pg.2]    [Pg.12]    [Pg.380]    [Pg.171]    [Pg.171]    [Pg.26]    [Pg.80]    [Pg.85]    [Pg.50]    [Pg.60]    [Pg.449]    [Pg.450]    [Pg.39]    [Pg.23]    [Pg.18]    [Pg.317]    [Pg.319]    [Pg.428]    [Pg.550]    [Pg.173]    [Pg.178]    [Pg.79]    [Pg.1136]    [Pg.323]    [Pg.432]    [Pg.508]   
See also in sourсe #XX -- [ Pg.11 ]



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