Cytochrome mitochondrial, half-life

Figure 1. The predicted consequences of one week of detraining and the time of retraining required to recover the full Increase In cytochrome c content (an index of mitochondrial content) In the working muscle. Note that In one week of Inactivity (approx. 1 half-life), nearly 50% of the training effect is lost. Similarly, each week of retraining recovers approx. 50% of the way toward the full training effect. Since the process exhibits first-order kinetics. It takes longer to recover fully. "Reproduced with permission from Ref. 56. Copyright 1977, New York Academy of Sciences. "...

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