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CYP2D6 gene polymorphisms

Wan YJ, Poland RE, Han G, Konishi T, Zheng YP, Berman N, Lin KM. Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in southern California, Pharmacogenetics 2001 11(6) 489-499. [Pg.84]

Fu, Y., Fan, C. H., Zhao, Z. H. et al. (2006a). Association of CYP2D6 gene C188T polymorphism with tardive dyskinesia (TD) in Chinese patients with schizophrenia. Chinese Journal of... [Pg.94]

Kimura S, Umeno M, Skoda RC, Meyer UA, Gonzalez FJ. 1989. The human debrisoquine 4-hydroxylase (CYP2D) locus sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am J Hum Genet 45 889-904. [Pg.85]

Actually, CY2D6 gene polymorphisms, associated with null or reduced enzyme activity, have been reported to negatively influence (in a gene-dose manner) the blood level of endoxifen in numerous prospective pharmacokinetic studies [11,172, 192-196], Some retrospective and prospective studies have shown that CYP2D6 polymorphism was associated with worse clinical outcomes in PMs and IMs patients in terms of recurrence and disease free survival or BC development in the chemo-prevention setting [192,194,195,197-205],... [Pg.225]

Klimkowicz-Mrowiec A, Wolkow P, Sado M, Dziubek A, Pera J, Dziedzic T et al (2013) Influence of rsl080985 single nucleotide polymorphism of the CYP2D6 gene on response to treatment with donepezil in patients with alzheimer s disease. Neuropsychiatr Dis Treat 9 1029-1033... [Pg.554]

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See also in sourсe #XX -- [ Pg.42 ]



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