Cyclopropanones, chemistry

Although cyclopropanones are very reactive compounds, several of them have been isolated. For reviews of cyclopropanone chemistry, see Wasserman, H.H. Clark, G.M. Turley, PC. Top. Curr. Chem., 1974, 47, 73 Turro, N.J. Acc. Chem. Res., 1969, 2, 25. 

H. H. Wasserman, G. M. Clark, and P. C. Turley, Recent Aspects of Cyclopropanone Chemistry," in Topics in Current Chemistry I, No. 47, Springer Verlag, New York, 1974. 

A significant step in studying the chemistry of cyclopropanones has resulted from the discovery that many labile carbonyl derivatives such as hemiacetals and carbinol amines are useful precursors of the parent ketone. 4-6> Such derivatives may be isolated, purified and used as cyclopropanone substitutes or, alternatively, may be generated in solution and used as in situ precursors. As a result of these advances, exploration of cyclopropanone chemistry has recently been accelerated. The aim of this article is to review some of this chemistry, noting areas where there may be potential applications in synthesis. 

In our discussion of cyclopropanone chemistry, much of the attention is devoted to derivatives of type 1 where X and Y are labile groups... 

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