Cyclopentane Ethylamine

Fig. 7-6). Two unichiral amides which have been known capable of this reaction are 1-phenylethylamine [15] and l-(l-naphthyl)ethylamine [16]. Marfey s reagent [N-a-(2,4-dinitro-5-fluorophenyl)-L-alaninamide] was introduced as a reagent to deriva-tize amino acids with cyclopentane, tetrahydroisoquinoline or tetraline structures [17]. Simple chiral alcohols such as 2-octanol can also be used to derivatize acids such as 2-chloro-3-phenylmethoxypropionic acid [18]. 

Cyclohexanol, Cyclopentane, Cyclopentene, 1,2-Dichloroethane, Diethyl phthalate, 1,4-Dioxane, Ethephon. Ethylamine, Ethylene dibromide, Ethylenimine, p-Propiolactone, Tetraethyl pyrophosphate, TCDD, 1,1,1-Trichloroethane, Trichloroethylene, Vinyl chloride Ethylene chlorohydrin, see Bis(2-chloroethyl) ether Ethylenediamine, see Ethylene thiourea. Maneb Ethylene glycol, see Bis(2-chloroethyl) ether, 1,2-Dichloroethane, Ethylene chlorohydrin. Ethylene dibromide... 

While initial attempts to hydrogenate ferrocene under relatively mild conditions were not successful, extensive treatment with hydrogen in the presence of a nickel catalyst at 300° to 350° and under 280-atm. absolute pressure results in the formation of cyclopentane (64). In contrast to the extreme resistance of ferrocene to catalytic hydrogenation, this aromatic-type compound can be readily reduced by lithium in ethylamine, the products being metallic iron and cyclopen tadiene (121). 

Removal of the iron from ferrocene has been accomplished by brief treatment (5 min) with lithium in ethylamine to give reasonable yields ( 70 %) of cyclopentadiene (Trifan and Nicholas, 1957). More recently, a hydrogenation procedure for ferrocenes employing Pd/C as catalyst under mild conditions (1 atm hydrogen, room temperature) but in acid solution (aqueous perchloric acid in acetic acid) has been reported as a synthetic route to substituted cyclopentanes. No yields were given (Van Meurs et a ., 1975). 

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