Cyclopalladated secondary

Miscellaneous Reactions of Phosphines. Procedures for the resolution of benzylcyclohexylphenylphosphine have been developed, involving adduct formation with cyclopalladated chiral amine complexes. A similar approach has also been used for the resolution of P-chiral secondary phosphines, e.g. (193). Treatment of t-butyl(di-o-tolyl)phosphine with potassium tetrachloro-palladate(ii) yields a cyclopalladated complex (194), involving chiral phos-... 

Cyclopalladation of the racemic secondary amine C6H4NHBu Me with Pd(OAc)2 in a mixture of benzene and glacial AcOH on heating gives a 3 1 mixture of regioisomeric complexes 50 and 51 (Scheme 13) Addition of excess acetic acid to this mixture led to the formation of a cyclopalladated imine complex. A related study with regard to the competition between sp and sp C-H bonds in cyclopalladation of A-G6H4NHBu Me was published in 2000. ... 

Secondary benzylamines have been cyclopalladated and reactions of the chloro-bridged complexes with various ligands such as PPhs, acac, 1,1,2,2-tetraacetylethane, l-phenylazo-2-naphthol, and 2-hydroxy-3-/-butyl-5-methylbenzylidene-/)-chloroaniline have been carried out. Secondary and primary benzylamines were cyclopalladated in benzene using Pd(OAc)2. Bridge-splitting reactions with, for example, 3,5-lutidine, PPh3, and thallium acetylacetonate have been carried out. 

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