Cyclododecanone, preparation from cyclododecanol

Nylon 12 first beeame available on a semieommercial scale in 1963. The monomer, dodecanelactam, is prepared from butadiene by a multistaged reaction. In one proeess butadiene is treated with a Ziegler-type eatalyst system to yield the cyclic trimer, cyclododeca-1, 5, 9-triene. This may then be hydrogenated to give cyelododeeane, which is then subjeeted to direct air oxidation to give a mixture of cyclododecanol and cyclododecanone. Treatment of the mixture with... 

Dodecanedioic acid is prepared from cyclododecene (obtained from butadiene) by methods which are entirely analogous to those used to prepare adipic acid from benzene (section 10.2.2(a)). The cyclododecene is reduced to cyclododecane, which is oxidized firstly to a mixture of cyclododecanol and cyclododecanone and then to dodecanedioic acid. Dodecanedioic acid is a colourless crystalline solid, m.p. 129°C. 

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