Cyclocholates

Bonar-Law and Saunders have demonstrated that cyclocholates (see 27 Figure 3.5) reversibly self-assemble in organic solvents to form short, molecular cylinders... 

Fig. 4 (a) The bowl-shaped receptor with four steroid units (Ref. [33]). (b) Singly capped cyclocholate-porphyrin receptor (Ref. [34])... 

Bonar-Low. R.P. Mackay, L.G. Sanders. J.K.M. Morphine recognition by a porphyrin cyclocholate molecular bowl. J. Chem. Soc.. Chem. Commun. 1993. 456. 

ABSTRACT. Syntheses and binding properties of some supermacrocyclic hosts based on porphyrins and steroids are presented. It is shown that the ligand-binding properties of linear intermediates can be used to control the outcome of the synthesis three distinct rdles for such ligand templates are identified and exploited in the synthesis of a linear poiphyrin octamer. Some chemistry of cyclocholates and cholate-capped poiphyrins is also described, with an emphasis on the control of ring size through steric effects. 

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