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Cyclo-oxygenase products, role

ROLE OF CYCLO-OXYGENASE PRODUCTS IN ENDOTOXAEMIA AND SEPSIS... [Pg.93]

NSAIDs exert their effects by inhibition of the enzyme cyclo-oxygenase (COX). This results in reduced production of prostaglandins and thromboxanes because COX normally catalyses their formation from arachidonic acid. Prostaglandins play a role in pain by sensitising sensory nerve endings to the effects of other mediators such as bradykinin. [Pg.245]


See other pages where Cyclo-oxygenase products, role is mentioned: [Pg.72]    [Pg.68]    [Pg.207]    [Pg.50]    [Pg.1372]    [Pg.8]    [Pg.245]    [Pg.8]    [Pg.28]    [Pg.34]    [Pg.37]    [Pg.41]    [Pg.78]    [Pg.130]    [Pg.145]    [Pg.73]    [Pg.75]    [Pg.368]   


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