2.3- cyclo dendralene sequence

Owing to their availability through cyclo-isomerization reactions, a number of studies describing DTDA reactions of 2,3-cyclo[3]dendralenes have been disclosed [20-22]. One example that perhaps best demonstrates the high levels of stereo- and chemoselectivity possible in such reaction sequences was published by Brummond and coworkers in 2006 (Scheme 12.16) [23]. In this... 

Scheme 12.16 A DTDA sequence of 2,3-cyclo[3]dendralene 81 developed by Brummond and coworkers.

Cyclo [3] dendralenes contain both a semicyclic and acyclic diene site, and, in principle, either of the two tricyclic frameworks 92 or 94 can be accessed through alternative DTDA sequences (Scheme 12.19). 

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