Cyclization of dihalides

This has been applied to the cyclization of dihalides [45, 46], nonconjugated, unsaturated ketones [47] and esters [48], oxoalkylpyridinium salts [49], aldehydes and unsaturated nitriles [50], halides, and unsaturated esters [51], The umpoled acceptors, mostly radical anions or carban-ions (see Scheme 1), can also be used in intermolecular reactions such as acylation, alkylation, or carboxylation (Eq. 5). 

The cyclization of dihalides with dithiols appears to represent a reasonably versatile approach to a number of dithiocins and their benzannelated analogues, in low-to-moderate yields. The sulfur... 

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