Cyclic voltammetry proteins effect

In the same sense, at negatively charged edge-plane graphite electrodes, faradaic response of plastocyanin is normally not obtained due to the repulsive coulombic interactions. However, upon addition of a small amount of a redox-inactive multivalent cation, i.e., Mg +, stable and well-behaved cyclic voltammetry is observed (35). Extensive investigations of anionic proteins revealed (27,36) that the effectiveness of promotion is in the order of s> M. These effects... 

Redox-active species that are immobilized on the electrode and undergo simple reversible electron transfer give rise to a peak-type cyclic voltammetry response that is not influenced by diffusion effects, but which is, instead, much more sensitive to the characteristic properties of the protein [1]. Provided the sample is homogeneous and there are no interactions between molecules in the layer, the peaks for oxidation and reduction should have the Nernstian characteristics defined by Laviron that is, they comprise finite passed charge with no tailing current, with a peak separation close to zero [29]. This is depicted in Fig. 3(a), where the capacitive background that is observed in real experiments is not shown. The peak widths... 

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