Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Ketone cyclic

The reaction proceeds most readily wfth alkylaryl, dialkyl, and cyclic ketones, but the crude product may contain some secondary or tertiary amine. [Pg.223]

By pyrolysis of dibasic acids or their salts to yield cyclic ketones. The slow distillation of adipic acid with about. 5 per cent, of baryta affords cyclo-pentanone in good yield ... [Pg.336]

The preparation of the cyclic ketone a-tetralone possesses a number of interesting features. Succinic anhydride is condensed with pure benzene in the presence of anhydrous aluminium chloride (slightly over two equivalents see 1 above) to yield (3-benzoylpropionlc acid ... [Pg.728]

Reaction of cyclic ketones with diazoraethane leads to ring enlargement. Thus cyctohexanone (I) (1 mol) and diazomethane (1 mol) give /oheptanone (II) in about 60 per cent, yield together with a little epoxide (III) as by product and some cj/cioootanone (IV) resulting from further reaction of cyctoheptanone with diazomethane. ... [Pg.946]

Compounds which dissolve in concentrated sulphuric acid may be further subdivided into those which are soluble in syrupy phosphoric acid (A) and those which are insoluble in this solvent (B) in general, dissolution takes place without the production of appreciable heat or colour. Those in class A include alcohols, esters, aldehydes, methyl ketones and cyclic ketones provided that they contain less than nine carbon atoms. The solubility limit is somewhat lower than this for ethers thus re-propyl ether dissolves in 85 per cent, phosphoric acid but re-butyl ether and anisole do not. Ethyl benzoate and ethyl malonate are insoluble. [Pg.1050]

Alcohols, esters (but not ethyl benzoate, ethyl malonate or ethyl oxalate), aldehydes, methyl ketones and cyclic ketones containing less than nine carbon atoms as well as ethers containing less than seven carbon atoms are soluble in 85 p>er cent, phosphoric acid. [Pg.1053]

An interesting aspect of this reaction is the contrasting stereoselective behaviour of the dimethyisulfonium and dimethyloxosuifonium methylides in reactions with cyclic ketones (E.J. Corey, 1963 B, 1965 A C.E. Cook, 1968). The small, reactive dimethyisulfonium ylide prefers axial attack, but with the larger, less reactive oxosulfonium ylide only the thermodynamically favored equatorial addition is observed. [Pg.45]

The 3.8-nonadienoate 91, obtained by dimerization-carbonylation, has been converted into several natural products. The synthesis of brevicomin is described in Chapter 3, Section 2.3. Another royal jelly acid [2-decenedioic acid (149)] was prepared by cobalt carbonyl-catalyzed carbonylation of the terminal double bond, followed by isomerization of the double bond to the conjugated position to afford 149[122], Hexadecane-2,15-dione (150) can be prepared by Pd-catalyzed oxidation of the terminal double bond, hydrogenation of the internal double bond, and coupling by Kolbe electrolysis. Aldol condensation mediated by an organoaluminum reagent gave the unsaturated cyclic ketone 151 in 65% yield. Finally, the reduction of 151 afforded muscone (152)[123]. n-Octanol is produced commercially as described beforc[32]. [Pg.445]

Oxy-Cope rearrangement of 56 to form the cyclic ketone 57 can be carried out at room temperature with catalysis by PdCl2(PhCN)2(47]. [Pg.535]

A standard synthetic sequence for building a six membered cyclic ketone onto an existing aromatic ring is shown in outline as follows Specify the reagents necessary for each step... [Pg.516]

Each of the compounds indicated undergoes an intramolecular Fnedel-Crafts acylation reac tion to yield a cyclic ketone Wnte the structure of the expected product in each case... [Pg.516]

With ketones the e ending of an alkane is replaced by one in the longest con tinuous chain containing the carbonyl group The chain is numbered in the direction that provides the lower number for this group The carbonyl carbon of a cyclic ketone is C 1 and the number does not appear m the name... [Pg.705]

The November 2001 issue of the Journal of Chemical Education ipp 1533-1534) describes an introductory biochemistry laboratory ex periment involving cycio hexanone monooxygenase oxidation of cyclic ketones... [Pg.738]

Compounds known as lactones which are cyclic esters are formed on Baeyer—Vilhger oxi dation of cyclic ketones Suggest a mechanism for the Baeyer—Vilhger oxidation shown... [Pg.749]

Some toxicological data for cyclic ketones are shown in Table 16. Interestingly, toxicity is shown to increase with ring size. This is in reverse order of relative reactivity. [Pg.501]

Table 16. Toxicological Properties of Cyclic Ketones Compared with Aliphatic Ketones ... Table 16. Toxicological Properties of Cyclic Ketones Compared with Aliphatic Ketones ...
Hypochlorous acid adds to oximes of cyclic ketones forming intermediate a-chloronitroso compounds that can be converted to nitro compounds (108). [Pg.467]

Preparation of spirooxaziridines from cyclic ketones poses no problems nor does oxaziridine synthesis from cyclic Schiff bases, which was preferably carried out with pyrro-lines to give, for example (245) (59JCS2102) and, in connection with tranquilizer synthesis, with heterocyclic seven-membered rings to give, for example, (246) (63JOC2459). [Pg.228]

We present here examples of this condensation with an aromatic aldehyde and a cyclic ketone. Both of these examples are useful because, although other methods are available for their preparation, problems often attend these syntheses. In the synthesis of cyclohexy11deneaceton1tr11e, for example, the standard method results exclusively In the g.y-lsomer and none of the a,g-Isomer. In Part A of this procedure, cyclohexanone Is condensed with acetonitrile to give predominantly the conjugated Isomer (80-83%) whicfi is then separated from the nonconjugated isomer by selective bromination. [Pg.184]

The procedure described is essentially that of Shioiri and Yamada. Diphenyl phosphorazidate is a useful and versatile reagent in organic synthesis. It has been used for racemlzatlon-free peptide syntheses, thiol ester synthesis, a modified Curtius reaction, an esterification of a-substituted carboxylic acld, formation of diketoplperazines, alkyl azide synthesis, phosphorylation of alcohols and amines,and polymerization of amino acids and peptides. - Furthermore, diphenyl phosphorazidate acts as a nitrene source and as a 1,3-dipole.An example in the ring contraction of cyclic ketones to form cycloalkanecarboxylic acids is presented in the next procedure, this volume. [Pg.188]

The present preparation illustrates a general and convenient irethod for ring contraction of cyclic ketones. The first step is the usual procedure for the preparation of enamines. The second step involves 1,3-dipolar cycloaddition of diphenyl phosphorazidate to an enamine followed by ring contraction with evolution of nitrogen. Ethyl acetate and tetrahydrofuran can be used as a solvent in place of toluene. Pyrrolidine enamines from various cyclic ketones smoothly undergo the reaction under similar reaction conditions. Diphenyl (cycloalkyl-1-pyrrolidinylmethylene)phosphoramidates with 5,6,7, and 15 members in the ring have been prepared in yields of 68-76%. [Pg.194]

In a 2-1. round-bottomed, 3-necked flask fitted with a stirrer and two large-bore condensers are placed 200 cc. of 50 per cent nitric acid and 0.25 g. of vanadium pentoxide. The flask is heated to 65-70° in a water bath (thermometer in water), and I cc. of cyclopentanone added. Oxidation is indicated by the production of brown fumes. The water bath is removed, and 42 g. (less the i cc.) of the cyclic ketone added from a dropping funnel through the condenser at the rate of a drop every three seconds. The heat of the reaction keeps the flask at about 70°. If the temperature drops, oxidation ceases until the ketone has accumulated, when it may proceed almost explosively. In such a case, or if the temperature is higher, much succinic acid is formed. After addition has been completed, the water bath... [Pg.90]

With cyclic ketones, the a-cleavage can also be followed by intramolecular bydn en abstraction that leads eventually to an unsaturated ring-opened aldehyde ... [Pg.756]

In cyclic ketones, the diradical intermediates can recombine, leading to isomerized ketones ... [Pg.763]


See other pages where Ketone cyclic is mentioned: [Pg.231]    [Pg.233]    [Pg.285]    [Pg.295]    [Pg.345]    [Pg.172]    [Pg.44]    [Pg.137]    [Pg.38]    [Pg.200]    [Pg.369]    [Pg.370]    [Pg.387]    [Pg.499]    [Pg.500]    [Pg.253]    [Pg.184]    [Pg.375]    [Pg.466]    [Pg.471]   
See also in sourсe #XX -- [ Pg.264 ]

See also in sourсe #XX -- [ Pg.113 , Pg.114 , Pg.191 ]

See also in sourсe #XX -- [ Pg.83 ]

See also in sourсe #XX -- [ Pg.56 ]

See also in sourсe #XX -- [ Pg.310 , Pg.449 ]

See also in sourсe #XX -- [ Pg.73 , Pg.319 ]

See also in sourсe #XX -- [ Pg.264 ]

See also in sourсe #XX -- [ Pg.1859 ]

See also in sourсe #XX -- [ Pg.28 , Pg.128 , Pg.370 , Pg.384 , Pg.396 , Pg.482 ]

See also in sourсe #XX -- [ Pg.48 , Pg.49 , Pg.50 , Pg.51 , Pg.52 , Pg.53 , Pg.54 , Pg.116 ]

See also in sourсe #XX -- [ Pg.996 ]

See also in sourсe #XX -- [ Pg.6 , Pg.313 , Pg.314 , Pg.332 , Pg.333 ]

See also in sourсe #XX -- [ Pg.56 ]

See also in sourсe #XX -- [ Pg.145 ]

See also in sourсe #XX -- [ Pg.72 , Pg.79 , Pg.84 , Pg.85 , Pg.100 , Pg.247 , Pg.252 , Pg.255 , Pg.263 , Pg.264 , Pg.265 , Pg.271 , Pg.275 , Pg.278 , Pg.279 , Pg.283 , Pg.287 , Pg.288 , Pg.289 , Pg.290 , Pg.295 , Pg.298 , Pg.303 , Pg.304 , Pg.305 , Pg.306 , Pg.307 , Pg.314 , Pg.318 , Pg.361 ]

See also in sourсe #XX -- [ Pg.36 , Pg.96 ]

See also in sourсe #XX -- [ Pg.105 ]

See also in sourсe #XX -- [ Pg.508 ]

See also in sourсe #XX -- [ Pg.17 ]

See also in sourсe #XX -- [ Pg.56 , Pg.621 , Pg.623 , Pg.1173 ]

See also in sourсe #XX -- [ Pg.5 ]

See also in sourсe #XX -- [ Pg.123 ]

See also in sourсe #XX -- [ Pg.158 ]




SEARCH



Acyclic and cyclic ketones

Alcohols cyclic ketones

Aliphatic and cyclic ketone

Alkylation of Cyclic Ketones and Related Compounds

Arenes ketones, cyclic

Aromatization ketones, cyclic

Aziridines with cyclic ketones

BORANES CYCLIC KETONES

Baeyer-Villiger Oxidation of Cyclic Ketones

Borohydrides, monoalkylreduction cyclic ketones

Butenes cyclic ketones

Carbenes cyclic ketones

Carbon cyclic ketones

Clemmensen reduction cyclic ketones

Cyclic Ketone Enolates

Cyclic a,P-unsaturated ketone

Cyclic aryl ketones yields

Cyclic diazo ketones

Cyclic epoxy ketone

Cyclic ketones 2-arylated

Cyclic ketones 3,5-substituted, hydride reductions

Cyclic ketones cyclohexanones

Cyclic ketones enantioselective fluorinations

Cyclic ketones fluorination

Cyclic ketones from dicarboxylic acids

Cyclic ketones from keto esters

Cyclic ketones macrocyclic

Cyclic ketones oxidative cleavage

Cyclic ketones reduction with Selectride

Cyclic ketones ring expansion with diazomethane

Cyclic ketones trifluoromethanesulfonate

Cyclic ketones, Beckmann rearrangements

Cyclic ketones, CIDNP

Cyclic ketones, Michael reactions

Cyclic ketones, autoxidation

Cyclic ketones, condensation

Cyclic ketones, condensation catalyzed

Cyclic ketones, copolymerization with

Cyclic ketones, decarbonylation

Cyclic ketones, decarbonylation irradiation

Cyclic ketones, determining

Cyclic ketones, formation

Cyclic ketones, formation intramolecular acylation

Cyclic ketones, preparation

Cyclic ketones, ring expansion

Cyclic ketones, « alkenals from

Cyclic ketones, « alkenals from states

Cycloalkanes, from cyclic ketones

Cycloketones s. Cyclones Ketones, cyclic

Cycloketones s. Ketones, cyclic

Cyclopropanes from cyclic ketones

Decarboxylation cyclic ketone synthesis

Deoxygenation cyclic ketones

Diazo compounds ketones, cyclic

Dicarboxylic acids ketones, cyclic, synthesis

Diels-Alder reactions of cyclic ketones

Esters from cyclic ketones

Ethylene ketones, cyclic

Ethylenealdehydes ketones, cyclic

Fluorescence cyclic ketones

Fluorinated cyclic ketones

Fluorinated cyclic ketones photolysis

Fluorination of cyclic ketones

From cyclic ketones

Hetero)Cyclic Ketones

Hexanediol, 2,5-dimethylnickel acetate cyclic ketone reduction

Homologization ketones, cyclic

Hydrogen abstraction, ketones cyclic systems

Hydrogenation cyclic ketone

Hydroxycarboxylic acids ketones, cyclic

INDEX cyclic ketones

Intersystem crossing cyclic ketones

Ketene Ketone photolysis, cyclic

Ketenes from cyclic ketones

Ketocarboxylic acid esters ketones, cyclic

Ketocarboxylic acids ketones, cyclic

Ketone cyclic aromatic

Ketone cyclic, ring size

Ketone peroxides, cyclic

Ketones 5-7-membered cyclic

Ketones cyclic 2-alkoxycarbonyl

Ketones cyclic amine

Ketones cyclic imines, reactions with

Ketones cyclic thioacetal formation

Ketones cyclic triketones

Ketones cyclic, 5-membered: synthesis

Ketones cyclic, oxidation

Ketones cyclic, photochemical reactions

Ketones cyclic, reduction

Ketones cyclic, resolution

Ketones cyclic, synthesis

Ketones mercaptals, cyclic

Ketones sulfoxides, cyclic

Ketones, 2-cyano cyclic

Ketones, a-diazo cyclic

Ketones, addition derivatives cyclic

Ketones, bicyclic => cyclic diketones

Ketones, cyclic => diesters

Ketones, cyclic => diketones

Ketones, cyclic => dinitriles

Ketones, cyclic acid yields

Ketones, cyclic diazomethane

Ketones, cyclic from alcohols

Ketones, cyclic from diesters

Ketones, cyclic reagents

Ketones, cyclic reduction with hydride

Ketones, cyclic ring expansion with

Ketones, cyclic, conjugated

Ketones, cyclic, conjugated alkenes

Ketones, cyclic, lactams from

Ketones, with Cyclic

Kinetic cyclic ketones

Lactams ketones, cyclic

Lactams, alkylation cyclic ketones

Lactones = • cyclic ketones

Lactones, from cyclic ketones

Lactonization of cyclic ketones

LiAlH cyclic ketones

Lithium aluminum hydride cyclic ketone reduction

Michael additions of cyclic ketones

Michael donors cyclic ketones

Molecular eliminations cyclic ketones

Nicolaou hydroxy-ketone reductive cyclic ether formation

Nitric oxide cyclic ketones

Nitriles ketones, cyclic

Of ketones cyclic

Organometallic compounds reactions with cyclic ketones

Other Cyclic Ketones

Oxidative of cyclic ketones

Oximes of Cyclic and Heterocyclic Ketones

Oxygen cyclic ketones

Pinacols cyclic ketones

Preparation of cyclic ketones

Pressure cyclic ketones

Quantum yield cyclic ketones

Rearrangement Reactions of Cyclic Unsaturated Ketones

Reduction of Cyclic Ketones

Ring Cleavage of Cyclic a-Nitro Ketones (Retro-Acylation)

Ring contraction ketones, cyclic

Ring expansion ketones, cyclic, with diazo

Simple Cyclic Ketones

Sodium borohydride cyclic ketone reduction

Stereochemistry of Cyclic Ketone Alkylation

Stereoselectivity cyclic ketones

Sulfone, methoxymethyl phenyl reaction with cyclic ketones

Unsaturated cyclic ketone

Unsaturated ketones cyclic, synthesis

© 2024 chempedia.info