Cyclic amines with organic azides

Functionalized aziridines, especially optically active ones, are important intermediates in organic synthesis. The reaction of cyclic sulfates prepared from homochiral diols with amines or azide ion provides an efficient route to homochiral aziridines (equation 56). Formation of aziridines from cyclic sufates occurs with inversion at the stereogenic center. The reaction of the cyclic sulfates with an excess of a primary amine gives /2-... 

New important organic mnltifunctionalized cyclic six- and seven-membered aUyKc amines and azides have been obtained via regio- and diastereoselective reaetions of cyclic MBH type adducts 303 with N-nucleophiles. We have found... 

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