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CXCR2 receptor angiogenesis

CXCR2 Is the Receptor for Angiogenic ELR+ CXC Chemokine-Mediated Angiogenesis... [Pg.322]

Wente, M.N., M.P. Keane, M.D. Burdick, H. Friess, M.W. Buchler, G.O. Ceyhan, FLA. Reber, R.M. Strieter, and O.J. Hines. Blockade of the chemokine receptor CXCR2 inhibits pancreatic cancer cell-induced angiogenesis. Cancer Lett 241 221-7, 2006. [Pg.147]

There is abundant evidence that the receptor CXCR2 regulates the angiogenic process in a number of model systems. Gene knockout or antibody blockade of CXCR2 prevented CXC chemokine-mediated angiogenesis in a corneal micropocket assay [2]. Subsequently, it was shown that blockade of CXCR2 function disrupted endothelial cell chemotaxis and tube formation... [Pg.156]

Cummings CJ, Martin TR, Frevert CW, et al. Expression and function of the che-mokine receptors CXCRl and CXCR2 in sepsis. J Immunol 1999 162 2341-2346. Koch AE, Polverini PJ, Kunkel SL, et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 1992 258 1798-1801. [Pg.217]


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See also in sourсe #XX -- [ Pg.8 ]




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Angiogenesis

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