CV, coefficient of variation

Figure 7.55 shows a plot of over 2000 2%DOPC/dodecane Pe measurements (10-6 cm/s units), each representing at least three intra-plate replicates, vs. the estimated standard deviations, o(Pe). Over 200 different drug-like compounds were measured. The %CV (coefficient of variation 100 x a(Pe)/Pe) is about 10% near Pe 10 x 10 6 cm/s, and slightly increases for higher values of permeability, but rapidly increases for Pe< 0.1 x 10 6 cm/s, as shown in Table 7.21. These statistics accurately reflect the errors that should be expected in general. For some molecules, such as caffeine and metoprolol, %CV has been typically about 3-6%. 

Table 1. Hg concentration profile by survey zones and upland/lowland delineation (CV coefficient of variation). ...

SD = standard deviation CV = coefficient of variation ND = not detected. aWith Triton X-45 as the internal standard. b10 pL injection volume. 

Std., standard surface treatment ISS, interfacial shear strength SD, one standard deviation CV, coefficient of variation. 

FIGURE 9 Hierarchy of, relationship between, and objectives and requirements for prevalidation [106], validation [62,63, 68], and standardization of analytical methods [62, 63, 67, 68,75,84] RSD = relative standard deviation, CV = coefficient of variation, SOP = standard operating procedure. 

Table 3.4.2 Validation data calculated from ten-fold analyses of a low-pool (left two data panels) and a high-pool (right two data panels) all concentrations are given in pmol/l. CV Coefficient of variation...

Column specifications expressed as (length X ID, particle size manufacturer) when reported in original publication. n = number of determinations LoD = limit of detection CV = coefficient of variation. 

Table 1 Metrological properties of methods used by the Choles- CV coefficient of variation, HDLC high-density lipoprotein cho-terol Reference Method Laboratory Network (CKMLN). 2 KM lesterol, SD standard deviation, LDLC low-density lipoprotein Secondary reference method, DCM designated comparison meth- cholesterol, NA not available od, IDMS isotope dilution mass spectroscopy, AK Abell-Kendall,...

LLE liquid-liquid extraction, SPE solid phase extraction, LPME liquid-phase microextraction, ESI electrospray ionization, APCI atmospheric pressure chemical ionization, SSI sonic spray ionization, Q quadrupole, QqQ triple quadrupole, TOF time-of-flight, IT ion trap, IS internal standard, CV coefficient of variation, MRE mean relative error, LOD limit of detection, LLOQ lower limit of quantification... 

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