Cu II and hydrogen peroxide in solution

Depolymerisation of hyaluronic acid induced by Cu(II) and hydrogen peroxide in solution 

Although in the absence of hyaluronic acid, dilute solutions of hydrogen peroxide remain relatively stable in the presence of cupric and chloride ions, when hyaluronic acid is also present, the hydrogen peroxide decomposes accompanied by the degradation of hyaluronic acid [91]. Fig. 4 shows the depolymerisation data as measured by low-angle laser-light scattering experiments. 

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