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Cryptotethia crypta

DNA, RNA and protein synthesis at concentrations close to those at which viral growth was inhibited and hence they have both low antiviral selectivity and therapeutic index. Some improvements in the therapeutic index have been achieved through structural modifications [156]. Two synthetic antiviral agents are currently under clinical use ara-A (9P-D-arabinofuranosyladenin, 200) and ara-C (1-P-D-arabinosyl-cytosine, 201) are related to the arabinosides isolated in the early 1950s from the marine sponge Cryptotethia crypta, (Table 10) [155]. [Pg.529]

Isol. from Caribbean sponge. Cryptotethia crypta. Antiviral agent. Mp 194-195°, Mp 242°. [a] +90 (c, 0.8 in Py). Low acute toxicity. [Pg.30]

MOL. WT. 112 MELTING point 335°C organism Cryptotethia crypta (Porifera) reference 36... [Pg.152]

See other pages where Cryptotethia crypta is mentioned: [Pg.263]    [Pg.263]    [Pg.320]    [Pg.175]    [Pg.171]    [Pg.757]    [Pg.122]    [Pg.160]    [Pg.162]    [Pg.163]    [Pg.263]    [Pg.263]    [Pg.320]    [Pg.175]    [Pg.171]    [Pg.757]    [Pg.122]    [Pg.160]    [Pg.162]    [Pg.163]   
See also in sourсe #XX -- [ Pg.175 ]

See also in sourсe #XX -- [ Pg.150 , Pg.153 , Pg.160 , Pg.162 , Pg.163 ]



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