Cryptopleurine, antitumour

S PS - 40S subunit site (cf. Cryptopleurine, Emetine Tvlocrebrine) [amoebicidal, antitumour, toxic]... 

Eagle s 9 KB carcinoma in cell culture (ED50 = 7-8 x 10 Pg/ml), but is inactive in vivo against a number of experimental neoplasms [41]. A bio-genetically-based synthesis of cryptopleurine has recently been described [42]. A number of analogues of (IV) have been synthesized for antitumour studies [42a]. 

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See also in sourсe #XX -- [ ]

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