Criteria setting and risk assessment

S. M., Sanderson, H., Sibley, P.K. and van den Brink, P.J. (2008) Extrapolation for criteria setting and risk assessment, in Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals, (eds... 

Extrapolation in the Context of Criteria Setting and Risk Assessment... 

For logistical reasons, it is frequently necessary to divide complex tasks into smaller components that can be more easily managed. The use of tiers or steps in the process of criteria setting and risk assessment is one method used to reduce complexity and narrow the focus of the process to the key issues, and it has been recommended frequently for use in risk assessments of pesticides (USEPA 1992, 1998 ... 

This chapter has outlined the general principles of the use of extrapolation in criteria setting and risk assessment. Extrapolation is used in the setting of criteria, where only effects are considered, as well as in risk assessments, where both effects and exposures are considered. In formulating approaches to criteria setting and risk assessment, tiers are often used to simplify the process. In keeping with the... 

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