Crinum erubescens

Similarly, from Crinum powellii, avoiding basic treatment, criwelline (241) was not obtained but the amorphous precriwelline (243) whose hydrochloride melted at 199-201° was isolated. The sequence leading from 243 to 245 and 247, the known alkaloid macronine (Vol. XI, p. 381), and its synthetic iV-demethyl derivative, respectively, established structure 243. The compound 247 was isolated from Crinum erubescens along with the carbamate 253 which probably arose from 247 during the extraction by the action of chloroform and ethanol. Epimacronine (246), another lactonic alkaloid of this series, was obtained in small amounts from 8. formosissima (50, 51). 

---