Chemomechanical coupling

Gens, A., Guitnaraes L. do N., Olivella, S. 2002. Coupled chemomechanical analysis for saturated and unsaturated soils. In Vulliet et al. (ed.). Environmental Geomechanics, Lausanne EPFL... 

Nishizaka, T., Oiwa, K., Noji, H., Kimura, S., Muneyuki, E., Yoshida, M., and Kinosita, K, Jr. (2004). Chemomechanical coupling in Fl-ATPase revealed by simultaneous observation of nucleotide kinetics and rotation. Nat. Struct. Mol. Biol. 11, 142-148. 

Based on a local dissolution law, the micromechanical approach is able to discuss the effects of the local heterogeneity of the mechanical affinity on the dissolution process and to predict the evolution of the pore space morphology. Whenever it is possible to describe the latter by a scalar parameter , (22) yields its evolution (t) which captures the chemomechanical coupling in so far as it controls the evolution of the poroelastic coefficients in (13). Nevertheless, the implementation of this modelling requires to be able to determine the microscopic strain state along the fluid-solid interface by appropriate micromechanical techniques. 

Chemomechanical coupling in the gastric H,K ATPase. Acta Physiol. Scand. 146,77-88. Bigelow, DJ. Inesi, G. (1992). Contributions of chemical derivatization and spectroscopic studies to the characterization of the Ca+ transport ATPase of sarcoplasmic reticulum. Biochim. Biophys. Acta 1113, 323-338. 

In this section, we first summarize the basic models used [67-69] for the description of kinesin and dynein motions driven by ATP hydrolysis. For both kinesin and dynein, two-dimensional master equations are used to describe the motion of the protein motors, although the variables represented by the two dimensions are different. In the case of kinesin, these two variables are used to describe the positions of the two motor domains and, for dynein, to be able to treat the variable chemomechanical coupling, one variable is used to describe its physical motion along the microtubule and the other used to describe its chemical coordinate. 

To account for the variations in the chemomechanical coupling ratio, a loose chemomechanical coupling model was introduced for dynein [67], in which two reaction coordinates were employed to describe the configuration change and translocation of dynein, respectively. The first coordinate was used to describe the conformation of the dynein that controls the ATP hydrolysis reaction and the second coordinate simply represents the location of a dynein on a microtubule. The first coordinate was called the chemical reaction coordinate (a) and the second the physical reaction coordinate (x). The details of the model include... 

A variable chemomechanical coupling mechanism of dynein may optimize its thermodynamic efficiency in its cargo transportation in cells [5,17,67], which was analyzed in Ref. [67] and is summarized in the following. The thermodynamic efficiency of a dynein can be calculated as... 

Nishiyama, M., Higuchi, H., and Yanagida, T. (2002) Chemomechanical coupling of the forward and backward steps of single kinesin molecules, Nat. Cell Biol. 4, 790-797. 

Pattern Formation in a Complex Reaction System by Chemomechanical Coupling... 

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