Cough drops/symp

Oxeladin [468-61-1] (54), an antitussive developed in the UK, is stmcturaHy related to carbetapentane in that the cyclopentane ring has been broken at the 3,4-bond. It is also similar pharmacologically. Extensive clinical studies using cough drops and symp containing oxeladin are described (73). The compound can be synthesized from phenylacetonitrile (74). 

The NF and reagent grades are employed in the pharmaceutical industry which makes use of benzyl alcohol s local anesthetic, antiseptic, and solvent properties (17—20). It also finds use in cough symps and drops ophthalmic solutions bum, dental (21), and insect repeUant solutions and ointments and dermatological aerosol sprays. It is used in nail lacquers and as a color developer in hair dyes by the cosmetics industry (22), and in acne treatment preparations (23). 

---