Cosmetic products, nitrosamine formation

A research program in progress at Raltech Scientific Services is designed to find inhibitors which will prevent nitrosamine formation in cosmetic products, A review of the literature (4) indicated that the oil phase of emulsions may play an important role in nitrosation chemistry. Thus, results from studies in water alone could be misleading when reduced to practice. 

Bronidox can be used as preservative for functional industrial fluids including cosmetics within a comparatively broad pH range (5-9). The average concentration is 01%. In terms of degradation and potential nitrosamine formation Bronidox and Bronopol behave analogously. Bronidox is mentioned in the EC list of preservatives for cosmetics (max. authorized concentration 01% limitations and requirements rinse-off products only avoid formation of nitro-samines). 

Occurrence of A-nitrosamino acids in cured meat products and their effect on formation of A-nitrosamines during heating Food Cosmet. Toxicol. 16 (1978) 343-348. 1933b. 

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