Coryphantha macromeris

Coryphantha comifera var. echinus Coryphantha elephanatidens Coryphantha macromeris Coryphantha macromeris var. runyonii Coryphantha pectinata... [Pg.105]

Coryphantha macromeris (Engelm.) Me-Synephr, Synephr, nor-Macr, calipamine, N-Me-calipamine Macr 226, 227... [Pg.119]

The most abundant alkaloid in Coryphantha macromeris, normacromerine, has been shown to originate from tyrosine (330). Tyramine and JV-methyltyramine are efficiently incorporated into normacromerine while octopamine and dopamine are poor precursors. Norepinephrine, epinephrine, normetanephrine, and meta-nephrine have all been shown to be biosynthetically incorporated into normacromerine, and they have also been shown to be naturally occurring trace intermediates in this cactus species (331, 334). Normacromerine is only slowly converted to macromerine in C. macromeris (332). The results indicate that alternative pathways to normacromerine exist precise conclusions regarding the biosynthesis of normacromerine must await further studies. [Pg.140]

Coryphantha macromeris (Cactaceae), Cyperus papyrus, C. rotundas (Cyperaceae), Citrus reticulata,... [Pg.181]

The j3-hydroxyphenethylamine synephrine (198) appears to arise in Citrus from tyrosine via tyramine and iV-methyltyramine. ° Normacromerine (199) and macromerine (200) are found in the cactus Coryphantha macromeris var. runyoniO Their genesis has also been studied.Specific incorporations of DL-[3- C]tyrosine, [l- C]tyramine, DL-[2- " C]dopa, and [l- CJdopamine into normacromerine established a pattern of biosynthesis similar to that of the other cactus alkaloids and again a C6-C2 unit is implicated. [This contrasts with the biosynthesis of the superficially similar base ephedrine (185), discussed above.]... [Pg.48]

The isolation, structure, synthesis, and absolute configuration of the new hydroxylic / -phenethylamine, (— )-macromerine (3), has been reported." The same cactus, Coryphantha macromeris, also contains (— )-normacromerine (4). ... [Pg.116]

Normacromerine.— Normacromerine (52) is closely related to simple phenethylamines/" and is formed from tyrosine and tyramine via epinephrine (50) in the cactus Coryphantha macromeris cf. ref. 9. Metanephrine (51), a natural constituent of the cactus, has been shown to be an efficient and specific precursor for normacromerine (52). The previously observed slow conversion of (52) into macromerine (53) has again been noted. ... [Pg.15]

Normacromerine.—The /8-hydroxy-phenethylamines, e.g. normacromerine (36), are closely related biosynthetically to phenethylamines. Both tyrosine and tyramine serve as precursors for (36) in Coryphantha macromeris var. runyonii, and so do norepinephrine (34) and epinephrine (35). A role for these compounds as intermediates in normacromerine biosynthesis is supported by their detection as normal constituents of the plant.A two-fold difference in the level of incorporation of (34) and (35) was interpreted as indicating separate pathways via these bases to (36), but firm conclusions must await further work. [Pg.7]

Normacromerine UiiHpNUs 211.26 101-103 -38.4° (CHCI3) Coryphantha macromeris, C. calipensis, C. greenwoodii, Desmodium tiliaefolium, Dolichothele longimamma 41787-64-8... [Pg.483]

The cactus Coryphantha macromeris alkaloid (/ )-macromerine that exhibits a hallucinogenic activity was synthesized in 50-73% yields and enantioselectivity 97— 99% ee by asymmetric transfer hydrogenation of dia-Ikylaminomethyl ketone 150 using RuCl[(/f,/f)-TsDPEN] (T -p-cymene) as a catalyst (Scheme 30.28). ... [Pg.933]

Thelocactus macromeris (Engelm.) L. Benson Coryphantha macromens Engelm.) Lem. (Cactaceae)... [Pg.505]

Coryphantha calipensis C. compacta C com era w . echinus C. macromeris C. palmerii C. ramiUosa (r. Note 7) C. macromeris and C. have been report-... [Pg.203]

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